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Honokiol Arrests Cell Cycle, Induces Apoptosis, and Potentiates the Cytotoxic Effect of Gemcitabine in Human Pancreatic Cancer Cells

Survival rates for patients with pancreatic cancer are extremely poor due to its asymptomatic progression to advanced and metastatic stage for which current therapies remain largely ineffective. Therefore, novel therapeutic agents and treatment approaches are desired to improve the clinical outcome....

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Autors principals: Arora, Sumit, Bhardwaj, Arun, Srivastava, Sanjeev K., Singh, Seema, McClellan, Steven, Wang, Bin, Singh, Ajay P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123370/
https://ncbi.nlm.nih.gov/pubmed/21720559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021573
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