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Stabilizing Salt-Bridge Enhances Protein Thermostability by Reducing the Heat Capacity Change of Unfolding

Most thermophilic proteins tend to have more salt bridges, and achieve higher thermostability by up-shifting and broadening their protein stability curves. While the stabilizing effect of salt-bridge has been extensively studied, experimental data on how salt-bridge influences protein stability curv...

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Detalles Bibliográficos
Main Authors: Chan, Chi-Ho, Yu, Tsz-Ha, Wong, Kam-Bo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123365/
https://ncbi.nlm.nih.gov/pubmed/21720566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021624
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