Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis

BACKGROUND: Collagen-containing leukocytes (CD45(+)Col-I(+)) accumulate in diseased and fibrotic tissues. However, the precise identity of these cells and whether injury is required for their recruitment remain unknown. Using a murine model of pulmonary fibrosis in which an inducible, bioactive form...

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Bibliographic Details
Main Authors: Peng, Xueyan, Mathai, Susan K, Murray, Lynne A, Russell, Thomas, Reilkoff, Ronald, Chen, Qingsheng, Gulati, Mridu, Elias, Jack A, Bucala, Richard, Gan, Ye, Herzog, Erica L
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123188/
https://ncbi.nlm.nih.gov/pubmed/21586112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-4-12
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