Serum Amyloid P Therapeutically Attenuates Murine Bleomycin-Induced Pulmonary Fibrosis via Its Effects on Macrophages

Macrophages promote tissue remodeling but few mechanisms exist to modulate their activity during tissue fibrosis. Serum amyloid P (SAP), a member of the pentraxin family of proteins, signals through Fcγ receptors which are known to affect macrophage activation. We determined that IPF/UIP patients ha...

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Detalhes bibliográficos
Main Authors: Murray, Lynne A., Rosada, Rogerio, Moreira, Ana Paula, Joshi, Amrita, Kramer, Michael S., Hesson, David P., Argentieri, Rochelle L., Mathai, Susan, Gulati, Mridu, Herzog, Erica L., Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837381/
https://ncbi.nlm.nih.gov/pubmed/20300636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009683
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