LFR1 Ferric Iron Reductase of Leishmania amazonensis Is Essential for the Generation of Infective Parasite Forms

The protozoan parasite Leishmania is the causative agent of serious human infections worldwide. The parasites alternate between insect and vertebrate hosts and cause disease by invading macrophages, where they replicate. Parasites lacking the ferrous iron transporter LIT1 cannot grow intracellularly...

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Autors principals: Flannery, Andrew R., Huynh, Chau, Mittra, Bidyottam, Mortara, Renato A., Andrews, Norma W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123093/
https://ncbi.nlm.nih.gov/pubmed/21558274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229674
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