TRAF7 Protein Promotes Lys-29-linked Polyubiquitination of IκB Kinase (IKKγ)/NF-κB Essential Modulator (NEMO) and p65/RelA Protein and Represses NF-κB Activation

Tumor necrosis factor receptor-associated factor (TRAF) proteins are cytoplasmic regulatory molecules that function as signal transducers for receptors involved in both innate and adaptive humoral immune responses. In this study, we show that TRAF7, the unique noncanonical member of the TRAF family,...

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Autores principales: Zotti, Tiziana, Uva, Antonio, Ferravante, Angela, Vessichelli, Mariangela, Scudiero, Ivan, Ceccarelli, Michele, Vito, Pasquale, Stilo, Romania
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123060/
https://ncbi.nlm.nih.gov/pubmed/21518757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215426
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