NF-κB Essential Modulator (NEMO) Is Critical for Thyroid Function

The I-κB kinase (IKK) subunit NEMO/IKKγ (NEMO) is an adapter molecule that is critical for canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, differentiation, cell growth, tumorigenesis, and apoptosis. To explore the functional role of canonical NF-κB signaling i...

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Vydáno v:J Biol Chem
Hlavní autoři: Reale, Carla, Iervolino, Anna, Scudiero, Ivan, Ferravante, Angela, D'Andrea, Luca Egildo, Mazzone, Pellegrino, Zotti, Tiziana, Leonardi, Antonio, Roberto, Luca, Zannini, Mariastella, de Cristofaro, Tiziana, Shanmugakonar, Muralitharan, Capasso, Giovambattista, Pasparakis, Manolis, Vito, Pasquale, Stilo, Romania
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786713/
https://ncbi.nlm.nih.gov/pubmed/26786105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.711697
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