TRAF7 Protein Promotes Lys-29-linked Polyubiquitination of IκB Kinase (IKKγ)/NF-κB Essential Modulator (NEMO) and p65/RelA Protein and Represses NF-κB Activation

Tumor necrosis factor receptor-associated factor (TRAF) proteins are cytoplasmic regulatory molecules that function as signal transducers for receptors involved in both innate and adaptive humoral immune responses. In this study, we show that TRAF7, the unique noncanonical member of the TRAF family,...

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Bibliographic Details
Main Authors: Zotti, Tiziana, Uva, Antonio, Ferravante, Angela, Vessichelli, Mariangela, Scudiero, Ivan, Ceccarelli, Michele, Vito, Pasquale, Stilo, Romania
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123060/
https://ncbi.nlm.nih.gov/pubmed/21518757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215426
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