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Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment

Bone morphogenetic protein (BMP) signaling regulates embryonic hematopoiesis via receptor-mediated activation of downstream SMAD proteins, including SMAD1. In previous work, we showed that Smad1 expression is sufficient to enhance commitment of mesoderm to hemangioblast fate. We also found indirect...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cook, Brandoch D., Liu, Susanna, Evans, Todd
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123019/
https://ncbi.nlm.nih.gov/pubmed/21515822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-312389
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