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Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment
Bone morphogenetic protein (BMP) signaling regulates embryonic hematopoiesis via receptor-mediated activation of downstream SMAD proteins, including SMAD1. In previous work, we showed that Smad1 expression is sufficient to enhance commitment of mesoderm to hemangioblast fate. We also found indirect...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123019/ https://ncbi.nlm.nih.gov/pubmed/21515822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-312389 |
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