Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells

BACKGROUND: A limitation in the number of insulin-producing pancreatic beta-cells is a special feature of diabetes. The identification of alternative sources for the induction of insulin-producing surrogate beta-cells is a matter of profound importance. PDX-1/VP16, BETA2/NeuroD, and MafA overexpress...

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Bibliografiske detaljer
Main Authors: You, Young-Hye, Ham, Dong-Sik, Park, Heon-Seok, Rhee, Marie, Kim, Ji-Won, Yoon, Kun-Ho
Format: Artigo
Sprog:Inglês
Udgivet: Korean Diabetes Association 2011
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122894/
https://ncbi.nlm.nih.gov/pubmed/21738894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2011.35.2.119
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