Combined Transfection of the Three Transcriptional Factors, PDX-1, NeuroD1, and MafA, Causes Differentiation of Bone Marrow Mesenchymal Stem Cells into Insulin-Producing Cells

Aims. The goal of cell transcription for treatment of diabetes is to generate surrogate β-cells from an appropriate cell line. However, the induced replacement cells have showed less physiological function in producing insulin compared with normal β-cells. Methods. Here, we report a procedure for in...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Qing-Song, Guo, Ming-Yan, Zhu, Lei, Wang, Xiang-Jun, Fan, Yu-Hua, Lu, Zhi-Wei, Wang, Sha-Jun, Zhu, Yao, Wang, Yan, Huang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Hindawi Publishing Corporation 2012
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385644/
https://ncbi.nlm.nih.gov/pubmed/22761608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/672013
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