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A Critical Threshold of Meningococcal Factor H Binding Protein Expression Is Required for Increased Breadth of Protective Antibodies Elicited by Native Outer Membrane Vesicle Vaccines

Native outer membrane vesicles (NOMV) (not detergent treated), which are prepared from recombinant strains with attenuated endotoxin activity and overexpressed factor H binding protein (fHbp), elicited broad serum bactericidal antibody responses in mice. The amount of overexpressed fHbp required for...

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Xehetasun bibliografikoak
Egile Nagusiak: Koeberling, Oliver, Delany, Isabel, Granoff, Dan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122520/
https://ncbi.nlm.nih.gov/pubmed/21367981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00542-10
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