A Critical Threshold of Meningococcal Factor H Binding Protein Expression Is Required for Increased Breadth of Protective Antibodies Elicited by Native Outer Membrane Vesicle Vaccines

Native outer membrane vesicles (NOMV) (not detergent treated), which are prepared from recombinant strains with attenuated endotoxin activity and overexpressed factor H binding protein (fHbp), elicited broad serum bactericidal antibody responses in mice. The amount of overexpressed fHbp required for...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Koeberling, Oliver, Delany, Isabel, Granoff, Dan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2011
Ämnen:
Vaccine Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122520/
https://ncbi.nlm.nih.gov/pubmed/21367981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00542-10
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk