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Effects of Etravirine Alone and with Ritonavir-Boosted Protease Inhibitors on the Pharmacokinetics of Dolutegravir

Dolutegravir (DTG) is an unboosted, once-daily integrase inhibitor currently in phase 3 trials. Two studies evaluated the effects of etravirine (ETR) alone and in combination with ritonavir (RTV)-boosted protease inhibitors (PIs) on DTG pharmacokinetics (PK) in healthy subjects. DTG 50 mg every 24 h...

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Hlavní autoři: Song, Ivy, Borland, Julie, Min, Sherene, Lou, Yu, Chen, Shuguang, Patel, Parul, Wajima, Toshihiro, Piscitelli, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122457/
https://ncbi.nlm.nih.gov/pubmed/21555764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00073-11
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