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Five-Minute Exposure to Caspofungin Results in Prolonged Postantifungal Effects and Eliminates the Paradoxical Growth of Candida albicans

We studied the impact of brief caspofungin exposures on postantifungal effects (PAFEs) and paradoxical effects for five Candida albicans isolates. In time-kill studies, caspofungin at 4× and 16× the MIC resulted in significant killing of all isolates. Caspofungin at 8 μg/ml resulted in lower levels...

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Bibliografiske detaljer
Main Authors: Shields, Ryan K., Nguyen, M. Hong, Press, Ellen G., Clancy, Cornelius J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122450/
https://ncbi.nlm.nih.gov/pubmed/21537017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00095-11
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