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Paradoxical Effect of Caspofungin against Candida Bloodstream Isolates Is Mediated by Multiple Pathways but Eliminated in Human Serum

Paradoxical growth of Candida in vitro at echinocandin concentrations exceeding the MIC is well described, but the clinical relevance is unknown. We assessed echinocandin paradoxical effects against Candida bloodstream isolates (BSI) in the presence or absence of human serum and investigated regulat...

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Detalhes bibliográficos
Main Authors: Shields, Ryan K., Nguyen, M. Hong, Du, Chen, Press, Ellen, Cheng, Shaoji, Clancy, Cornelius J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101391/
https://ncbi.nlm.nih.gov/pubmed/21422223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00999-10
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