Selective Membrane Disruption: Mode of Action of C16G2, a Specifically Targeted Antimicrobial Peptide

The specifically targeted antimicrobial peptide (STAMP) C16G2 was developed to target the cariogenic oral pathogen Streptococcus mutans. Because the design of this peptide was novel, we sought to better understand the mechanism through which it functioned. Compared to antimicrobial peptides (AMPs) w...

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Autors principals: Kaplan, Christopher W., Sim, Jee Hyun, Shah, Kevin R., Kolesnikova-Kaplan, Aida, Shi, Wenyuan, Eckert, Randal
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122425/
https://ncbi.nlm.nih.gov/pubmed/21518845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00342-11
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