Selective Membrane Disruption: Mode of Action of C16G2, a Specifically Targeted Antimicrobial Peptide

The specifically targeted antimicrobial peptide (STAMP) C16G2 was developed to target the cariogenic oral pathogen Streptococcus mutans. Because the design of this peptide was novel, we sought to better understand the mechanism through which it functioned. Compared to antimicrobial peptides (AMPs) w...

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Bibliographic Details
Main Authors: Kaplan, Christopher W., Sim, Jee Hyun, Shah, Kevin R., Kolesnikova-Kaplan, Aida, Shi, Wenyuan, Eckert, Randal
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122425/
https://ncbi.nlm.nih.gov/pubmed/21518845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00342-11
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