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Molecular Chaperone Hsp104 Can Promote Yeast Prion Generation
[URE3] is an amyloid-based prion of Ure2p, a regulator of nitrogen catabolism in Saccharomyces cerevisiae. The Ure2p of the human pathogen Candida albicans can also be a prion in S. cerevisiae. We find that overproduction of the disaggregating chaperone, Hsp104, increases the frequency of de novo [U...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122315/ https://ncbi.nlm.nih.gov/pubmed/21467567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.127779 |
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