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[URE3] Prion Propagation in Saccharomyces cerevisiae: Requirement for Chaperone Hsp104 and Curing by Overexpressed Chaperone Ydj1p

The [URE3] nonchromosomal genetic element is an infectious form (prion) of the Ure2 protein, apparently a self-propagating amyloidosis. We find that an insertion mutation or deletion of HSP104 results in inability to propagate the [URE3] prion. Our results indicate that Hsp104 is a common factor in...

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Bibliografiset tiedot
Päätekijät: Moriyama, Hiromitsu, Edskes, Herman K., Wickner, Reed B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC86546/
https://ncbi.nlm.nih.gov/pubmed/11073991
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