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[URE3] Prion Propagation in Saccharomyces cerevisiae: Requirement for Chaperone Hsp104 and Curing by Overexpressed Chaperone Ydj1p

The [URE3] nonchromosomal genetic element is an infectious form (prion) of the Ure2 protein, apparently a self-propagating amyloidosis. We find that an insertion mutation or deletion of HSP104 results in inability to propagate the [URE3] prion. Our results indicate that Hsp104 is a common factor in...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Moriyama, Hiromitsu, Edskes, Herman K., Wickner, Reed B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2000
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8916-8922.2000
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