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Dislocation of Ricin Toxin A Chains in Human Cells Utilizes Selective Cellular Factors
Ricin is a potent A-B toxin that is transported from the cell surface to the cytosol, where it inactivates ribosomes, leading to cell death. Ricin enters cells via endocytosis, where only a minute number of ricin molecules reach the endoplasmic reticulum (ER) lumen. Subsequently, the ricin A chain t...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122183/ https://ncbi.nlm.nih.gov/pubmed/21527639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234708 |
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