TRAM1 Participates in Human Cytomegalovirus US2- and US11-mediated Dislocation of an Endoplasmic Reticulum Membrane Glycoprotein

The human cytomegalovirus proteins US2 and US11 have co-opted endoplasmic reticulum (ER) quality control to facilitate the destruction of major histocompatibility complex class I heavy chains. The class I heavy chains are dislocated from the ER to the cytosol, where they are deglycosylated and subse...

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Bibliographic Details
Main Authors: Oresic, Kristina, Ng, Caroline L., Tortorella, Domenico
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Membrane Transport, Structure, Function, and Biogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645836/
https://ncbi.nlm.nih.gov/pubmed/19121997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807568200
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