Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12

Disturbance of calcium homeostasis and accumulation of misfolded proteins in the endoplasmic reticulum (ER) are considered contributory components of cell death after ischemia. However, the signal-transducing events that are activated by ER stress after cerebral ischemia are incompletely understood....

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Detalhes bibliográficos
Main Authors: Badiola, N, Penas, C, Miñano-Molina, A, Barneda-Zahonero, B, Fadó, R, Sánchez-Opazo, G, Comella, J X, Sabriá, J, Zhu, C, Blomgren, K, Casas, C, Rodríguez-Alvarez, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122062/
https://ncbi.nlm.nih.gov/pubmed/21525936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.31
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