A carregar...
UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
BiP is a major ER chaperone and suggested to act as primary sensor in the activation of the unfolded protein response (UPR). How BiP operates as a molecular chaperone and as an ER stress sensor is unknown. Here, by reconstituting components of human UPR, ER stress and BiP chaperone systems, we disco...
Na minha lista:
| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858872/ https://ncbi.nlm.nih.gov/pubmed/31695187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0324-9 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|