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Bone Morphogenetic Protein-6 Promotes Cerebellar Granule Neurons Survival by Activation of the MEK/ERK/CREB Pathway

Bone morphogenetic proteins (BMPs) have been implicated in the generation and postnatal differentiation of cerebellar granule cells (CGCs). Here, we examined the eventual role of BMPs on the survival of these neurons. Lack of depolarization causes CGC death by apoptosis in vivo, a phenomenon that is...

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Detalhes bibliográficos
Main Authors: Barneda-Zahonero, Bruna, Miñano-Molina, Alfredo, Badiola, Nahuai, Fadó, Rut, Xifró, Xavier, Saura, Carlos A., Rodríguez-Alvarez, José
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793283/
https://ncbi.nlm.nih.gov/pubmed/19846661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-05-0424
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