Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

Prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)/Cas (CRISPR-associated sequences) systems provide adaptive immunity against viruses when a spacer sequence of small CRISPR RNA (crRNA) matches a protospacer sequence in the viral genome. Viruses that escape CRISPR/Cas resi...

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Main Authors: Semenova, Ekaterina, Jore, Matthijs M., Datsenko, Kirill A., Semenova, Anna, Westra, Edze R., Wanner, Barry, van der Oost, John, Brouns, Stan J. J., Severinov, Konstantin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121866/
https://ncbi.nlm.nih.gov/pubmed/21646539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104144108
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