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Evolutionarily conserved surface residues constitute actin binding sites of tropomyosin

Tropomyosin (Tm) is a two-chained, α-helical coiled-coil protein that associates end-to-end to form a continuous strand along actin filaments and regulates the functions and stability of actin in eukaryotic muscle and nonmuscle cells. Mutations in Tm cause skeletal and cardiac myopathies. We applied...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Barua, Bipasha, Pamula, Melissa C., Hitchcock-DeGregori, Sarah E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121822/
https://ncbi.nlm.nih.gov/pubmed/21642532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101221108
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