On–off system for PI3-kinase–Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)

Nitric oxide (NO) physiologically regulates numerous cellular responses through S-nitrosylation of protein cysteine residues. We performed antibody-array screening in conjunction with biotin-switch assays to look for S-nitrosylated proteins. Using this combination of techniques, we found that phosph...

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Detalhes bibliográficos
Main Authors: Numajiri, Naoki, Takasawa, Kumi, Nishiya, Tadashi, Tanaka, Hirotaka, Ohno, Kazuki, Hayakawa, Wataru, Asada, Mariko, Matsuda, Hiromi, Azumi, Kaoru, Kamata, Hideaki, Nakamura, Tomohiro, Hara, Hideaki, Minami, Masabumi, Lipton, Stuart A., Uehara, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121815/
https://ncbi.nlm.nih.gov/pubmed/21646525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103503108
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