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A siRNA-Based Screen for Genes Involved in Chromosome End Protection

Telomeres are nucleoprotein complexes which protect the ends of linear chromosomes from detection as DNA damage and provide a sequence buffer against replication-associated shortening. In mammals, telomeres consist of repetitive DNA sequence (TTAGGG) and associated proteins. The telomeric core compl...

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Bibliografiske detaljer
Main Authors: Lackner, Daniel H., Durocher, Daniel, Karlseder, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121770/
https://ncbi.nlm.nih.gov/pubmed/21760879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021407
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