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Chemical synthesis of RNA using fast oligonucleotide deprotection chemistry.

The exocyclic amine protecting groups in oligonucleotide synthesis which require 8-16 hours at 55 degrees C for deprotection in ammonia have been replaced with more labile base protecting groups (dimethylformamidine for adenine and guanine and isobutyryl for cytosine). Using these fast oligonucleoti...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Nucleic Acids Res
Ngā kaituhi matua: Vinayak, R, Anderson, P, McCollum, C, Hampel, A
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 1992
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373236/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.6.1265
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