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Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene.

A large proportion of mutations at the human hprt locus result in aberrant splicing of the hprt mRNA. We have been able to relate the mutation to the splicing abnormality in 30 of these mutants. Mutations at the splice acceptor sites of introns 4, 6 and 7 result in splicing out of the whole of the d...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Steingrimsdottir, H, Rowley, G, Dorado, G, Cole, J, Lehmann, A R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1992
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.6.1201
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