Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphoma

Abstract Background The aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the diagnosis and treatment of B cell malignancies. With 4.3% of all new cancers diagnosed as Non-Hodgkin lymphoma, finding new biomarkers for the...

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Autores principales:	Michelle H. Townsend, Zac E. Ence, Taylor P. Cox, John E. Lattin, Weston Burrup, Michael K. Boyer, Stephen R. Piccolo, Richard A. Robison, Kim L. O’Neill
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2020-08-01
Colección:	Cancer Cell International
Materias:	Hypoxanthine Guanine Phosphoribosyltransferase (HPRT or HGPRT) Burkitt’s B cell lymphoma Acute Lymphoblastic Leukemia ALL Raji Lymphocytes
Acceso en línea:	http://link.springer.com/article/10.1186/s12935-020-01457-8
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