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Variant Identification in Multi-Sample Pools by Illumina Genome Analyzer Sequencing

Multi-sample pooling and Illumina Genome Analyzer (GA) sequencing allows high throughput sequencing of multiple samples to determine population sequence variation. A preliminary experiment, using the RET proto-oncogene as a model, predicted ≤30 samples could be pooled to reliably detect singleton va...

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Detalhes bibliográficos
Main Authors: Margraf, Rebecca L., Durtschi, Jacob D., Dames, Shale, Pattison, David C., Stephens, Jack E., Voelkerding, Karl V.
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Biomolecular Resource Facilities 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121147/
https://ncbi.nlm.nih.gov/pubmed/21738440
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