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Multi-Sample Pooling and Illumina Genome Analyzer Sequencing Methods to Determine Gene Sequence Variation for Database Development

Determination of sequence variation within a genetic locus to develop clinically relevant databases is critical for molecular assay design and clinical test interpretation, so multisample pooling for Illumina genome analyzer (GA) sequencing was investigated using the RET proto-oncogene as a model. S...

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Detalhes bibliográficos
Main Authors: Margraf, Rebecca L., Durtschi, Jacob D., Dames, Shale, Pattison, David C., Stephens, Jack E., Mao, Rong, Voelkerding, Karl V.
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Biomolecular Resource Facilities 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922832/
https://ncbi.nlm.nih.gov/pubmed/20808642
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