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Overlapping roles and collective requirement for the co-receptors Gas1, Cdo and Boc in Shh pathway function
Secreted Hedgehog (Hh) ligands signal through the canonical receptor Patched (Ptch1). However, recent studies implicate three additional Hh-binding, cell surface proteins, Gas1, Cdo and Boc, as putative co-receptors for Hh ligands. A central question is to what degree these co-receptors function sim...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121104/ https://ncbi.nlm.nih.gov/pubmed/21664576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.04.018 |
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