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In vitro Evolution of Ligands to the Membrane Protein Caveolin

Membrane proteins comprise a third of the human genome, yet present challenging targets for reverse chemical genetics. For example, though implicated in numerous diseases including multiple myeloma, the membrane protein caveolin-1 appears to offer a poor target for the discovery of synthetic ligands...

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Détails bibliographiques
Auteurs principaux: Majumdar, Sudipta, Hajduczki, Agnes, Vithayathil, Rosemarie, Olsen, Tivoli J., Spitler, Ryan M., Mendez, Aaron S., Thompson, Travis D., Weiss, Gregory A.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120933/
https://ncbi.nlm.nih.gov/pubmed/21615158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201792q
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