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STAT6 Activation in Ulcerative Colitis: A New Target for Prevention of IL-13-Induced Colon Epithelial Cell Dysfunction
BACKGROUND: Interleukin 13 (IL-13) is upregulated in ulcerative colitis (UC) and increases colon epithelial permeability by inducing apoptosis and expression of the pore-forming tight junction protein claudin-2. IL-13 induces activation of signal transducer and activator of transcription 6 (STAT6)....
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120916/ https://ncbi.nlm.nih.gov/pubmed/21308881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21628 |
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