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The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression
BACKGROUND: Infection with high-risk human papillomaviruses (HPVs) such as HPV-16 is intimately associated with squamous cell carcinomas (SCCs) of the anogenital tract and a subset of oropharyngeal carcinomas. Such lesions, including pre-invasive precursors, frequently show multipolar mitoses and an...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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BioMed Central
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120798/ https://ncbi.nlm.nih.gov/pubmed/21609466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-61 |
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