Restriction of Advanced Glycation End Products Improves Insulin Resistance in Human Type 2 Diabetes: Potential role of AGER1 and SIRT1

OBJECTIVE: Increased oxidative stress (OS) and impaired anti-OS defenses are important in the development and persistence of insulin resistance (IR). Several anti-inflammatory and cell-protective mechanisms, including advanced glycation end product (AGE) receptor-1 (AGER1) and sirtuin (silent mating...

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Detalhes bibliográficos
Main Authors: Uribarri, Jaime, Cai, Weijing, Ramdas, Maya, Goodman, Susan, Pyzik, Renata, Chen, Xue, Zhu, Li, Striker, Gary E., Vlassara, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120204/
https://ncbi.nlm.nih.gov/pubmed/21709297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-0091
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