Salsalate Attenuates Free Fatty Acid–Induced Microvascular and Metabolic Insulin Resistance in Humans

OBJECTIVE: Insulin recruits muscle microvasculature, thereby increasing endothelial exchange surface area. Free fatty acids (FFAs) cause insulin resistance by activating inhibitor of κB kinase β. Elevating plasma FFAs impairs insulin’s microvascular and metabolic actions in vivo. Whether salsalate,...

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Bibliografske podrobnosti
Main Authors: Chai, Weidong, Liu, Jia, Jahn, Linda A., Fowler, Dale E., Barrett, Eugene J., Liu, Zhenqi
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2011
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120177/
https://ncbi.nlm.nih.gov/pubmed/21617098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-2345
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