Salsalate Attenuates Free Fatty Acid–Induced Microvascular and Metabolic Insulin Resistance in Humans

OBJECTIVE: Insulin recruits muscle microvasculature, thereby increasing endothelial exchange surface area. Free fatty acids (FFAs) cause insulin resistance by activating inhibitor of κB kinase β. Elevating plasma FFAs impairs insulin’s microvascular and metabolic actions in vivo. Whether salsalate,...

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Hlavní autoři: Chai, Weidong, Liu, Jia, Jahn, Linda A., Fowler, Dale E., Barrett, Eugene J., Liu, Zhenqi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2011
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120177/
https://ncbi.nlm.nih.gov/pubmed/21617098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-2345
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