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Free Fatty Acids Induce Insulin Resistance in Both Cardiac and Skeletal Muscle Microvasculature in Humans

CONTEXT: Insulin recruits microvasculature in both cardiac and skeletal muscle, which increases the endothelial exchange surface area. Plasma concentrations of free fatty acids (FFAs) are elevated in patients with diabetes, which impairs insulin-mediated skeletal muscle microvascular recruitment. OB...

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Bibliographic Details
Main Authors: Liu, Jia, Jahn, Linda A., Fowler, Dale E., Barrett, Eugene J., Cao, Wenhong, Liu, Zhenqi
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048322/
https://ncbi.nlm.nih.gov/pubmed/21047922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-1174
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