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Isolation of dominant negative mutants and inhibitory antisense RNA sequences by expression selection of random DNA fragments.
Selective inhibition of specific genes can be accomplished using genetic suppressor elements (GSEs) that encode antisense RNA, dominant negative mutant proteins, or other regulatory products. GSEs may correspond to partial sequences of target genes, usually identified by trial and error. We have use...
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| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1992
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312009/ https://ncbi.nlm.nih.gov/pubmed/1531871 |
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