Loading...

Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats

Sustained morphine treatment has been shown to produce paradoxical pain sensitization (opioid-induced hyperalgesia) and also causes increase in spinal pain neurotransmitter, such as calcitonin gene related peptide (CGRP), concentration in experimental animals. Studies have also shown that cyclic ade...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Tumati, S, Roeske, WR, Largent-Milnes, TM, Vanderah, TW, Varga, EV
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120016/
https://ncbi.nlm.nih.gov/pubmed/21571003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2011.04.036
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!