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Reconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activities

The error-free repair of double-strand DNA breaks by homologous recombination (HR) ensures genomic stability using undamaged homologous sequence to copy genetic information. While some of the aspects of the initial steps of HR are understood, the molecular mechanisms underlying events downstream of...

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Detalles Bibliográficos
Main Authors: Sebesta, Marek, Burkovics, Peter, Haracska, Lajos, Krejci, Lumir
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119790/
https://ncbi.nlm.nih.gov/pubmed/21565563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.03.003
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