Matrix Metalloproteinases are Associated with Increased Blood-Brain Barrier Opening in Vascular Cognitive Impairment

BACKGROUND AND PURPOSE: Subcortical ischemic vascular disease (SIVD) is a major form of vascular cognitive impairment (VCI) due to small vessel disease. Matrix metalloproteinases (MMPs) are neutral proteases that disrupt the blood-brain barrier (BBB) and degrade myelin basic protein under conditions...

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Detalhes bibliográficos
Main Authors: Candelario-Jalil, Eduardo, Thompson, Jeffrey, Taheri, Saeid, Grossetete, Mark, Adair, John, Edmonds, Elaine, Prestopnik, Jillian, Wills, John, Rosenberg, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119779/
https://ncbi.nlm.nih.gov/pubmed/21454822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.600825
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