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Early Beneficial Effect of Matrix Metalloproteinase Inhibition on BBB Permeability as Measured by MRI Countered by Impaired Long-Term Recovery After Stroke in Rat Brain
Proteolytic disruption of the extracellular matrix with opening of the blood-brain barrier (BBB) due to MMPs occurs in reperfusion injury after stroke. MMP inhibition blocks the early disruption of the BBB, but the long-term consequences of short-term MMP inhibition are not known. Recently, a method...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2330167/ https://ncbi.nlm.nih.gov/pubmed/17700631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600534 |
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