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Aggregation and Secondary Loop Structure of Oligonucleotides do not Determine Their Ability to Inhibit TLR9

Toll-like receptor 9 (TLR9) is an endosomal DNA sensor that warns us of the presence of infectious danger and triggers a rapid pro-inflammatory response in dendritic cells, macrophages and B cells. The consequences of uncontrolled TLR9 activation can be detrimental for the host, contributing to the...

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Sonraí Bibleagrafaíochta
Main Authors: Ashman, Robert F., Goeken, J. Adam, Lenert, Petar S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119753/
https://ncbi.nlm.nih.gov/pubmed/21376154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2011.02.023
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