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Aggregation and Secondary Loop Structure of Oligonucleotides do not Determine Their Ability to Inhibit TLR9
Toll-like receptor 9 (TLR9) is an endosomal DNA sensor that warns us of the presence of infectious danger and triggers a rapid pro-inflammatory response in dendritic cells, macrophages and B cells. The consequences of uncontrolled TLR9 activation can be detrimental for the host, contributing to the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119753/ https://ncbi.nlm.nih.gov/pubmed/21376154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2011.02.023 |
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